Paris is among 16 regions of France facing new lockdowns from midnight on Friday, the country’s prime minister Jean Castex has announced.
The measures will be in place for at least four weeks and will be less restrictive than those last March and November.
Schools will remain open and outdoor activities will be allowed to go ahead within a 10km radius of a person’s home.
Non-essential shops, not including book shops, will be required to close.
Inter-regional travel will be prohibited, and the nationwide nightly curfew will be moved back an hour to 7pm local time (6pm GMT).
French authorities have gone to great lengths to avoid re-imposing the strictest measures, having previously relied on weekend lockdowns and nightly curfews instead.
Skyrocketing COVID case numbers, however, along with a slow vaccine rollout, has forced the government to bolster its strategy.
It comes as France on Thursday reported a further 34,998 cases of COVID-19 – down slightly from the more than 38,000 new infections the day before.
Another 268 people have also died, bringing the country’s total fatality toll to 91,679.
Speaking on Thursday evening, Mr Castex said France was battling its third wave due to virus variants accelerating transmission across the nation.
“The moment has come to go further, with more demanding restrictions where things are most critical,” he said.
France was also one of about a dozen European countries that suspended the rollout of the Oxford/AstraZeneca vaccine earlier this week, citing concerns over reports of people developing blood clots after the jab.
However, Mr Castex said the rollout would resume on Friday afternoon – and confirmed he would receive the vaccine then, too.
“The AstraZeneca COVID-19 vaccine is effective, as underlined by the European regulator,” he said in reference to an earlier statement made by the European Medicines Agency (EMA).
He added: “It only has relatively rare side effects… it has a positive risk/reward ratio.”
The EMA has reviewed data related to concerns about the AstraZeneca vaccine, and declared it on Thursday to be “safe and effective”.
It said the benefits of getting inoculated would outweigh the possible risks, noting that the jab was not linked to an “overall risk” of blood clots.
Germany, Italy, Spain, Portugal, Latvia and Lithuania are among other countries that have said they would resume their respective rollouts after the EMA statement, while a decision from Ireland is expected on Friday.